Easy Cheesy Chicken, Spinach, and Artichoke Lasagna Recipe

Layers of comfort and flavor collide in this mouthwatering cheesy chicken, spinach, and artichoke lasagna that redefines classic Italian comfort food.

Creamy textures and bold ingredients dance together in each carefully crafted bite.

Tender chicken mingles with vibrant spinach and hearty artichokes, creating a symphony of taste sensations.

Melted cheese cascades between perfectly cooked pasta sheets, promising a truly indulgent experience.

The combination of classic Italian techniques with unexpected ingredients makes this dish a standout crowd-pleaser.

Every forkful delivers a rich, satisfying blend of textures and tastes that will have everyone asking for seconds.

Prepare to savor a lasagna that breaks all the traditional rules and delights the senses.

Why You’ll Love Chicken Spinach Artichoke Lasagna

• Quick Comfort Meal: Effortlessly transforms classic spinach and artichoke dip into a hearty, crowd-pleasing lasagna that brings everyone together.
• Versatile Cooking Style: Allows flexible preparation with simple layering technique, making it perfect for both novice and experienced home cooks who want a delicious, stress-free dinner.
• Nutrition-Packed Dish: Combines protein-rich chicken, nutrient-dense spinach, and artichokes into a single satisfying meal that delivers flavor and wholesome ingredients in every bite.
• Easy Entertaining Option: Ideal for potlucks, family gatherings, or weeknight dinners, this lasagna impresses guests while requiring minimal complex cooking skills.

Ingredients for Chicken Spinach Artichoke Lasagna

• Chicken: Tender protein packed with flavor.
• Spinach: Vibrant green vegetable with nutrients.
• Artichokes: Delicate and hearty vegetable with unique texture.
• Lasagna Noodles: Classic pasta for layering deliciousness.

• Ricotta Cheese: Creamy and soft Italian cheese.
• Mozzarella Cheese: Melty and stretchy white cheese.
• Parmesan Cheese: Sharp and salty aged cheese.

• Butter, Flour: Base for creating smooth white sauce.
• Milk: Liquid for creating creamy sauce.
• Garlic: Aromatic flavor enhancer.
• Salt, Pepper: Classic seasoning for balanced taste.

• Parsley, Extra Parmesan: Fresh herb and cheese for final touch.

How to Assemble the Chicken Artichoke Lasagna

Step 1: Warm Up the Oven

Crank the oven to a toasty 375°F and give your 9×13-inch baking dish a quick spray of cooking oil to prevent any sticky situations.

Step 2: Create a Creamy Sauce Base

Grab a skillet and melt butter over medium heat.

Toss in minced garlic and let it dance for a minute.

Sprinkle flour and continue cooking, stirring constantly to create a smooth foundation.

Step 3: Build the Sauce

Slowly pour in milk, whisking continuously to avoid any lumpy surprises.

Season with salt and pepper.

Let the mixture simmer and thicken for 2-4 minutes until it reaches a silky consistency.

Step 4: Add Cheesy Goodness

Stir in parmesan cheese until it melts completely and creates a luxurious sauce.

• Cooked chicken
• Fresh spinach
• Chopped artichoke hearts

Step 5: Layer Like a Lasagna Pro

• Thin layer of chicken mixture
• Lasagna noodles
• Ricotta cheese
• Another layer of chicken mixture
• Sprinkle of mozzarella

Repeat these layers, making sure to end with a generous topping of mozzarella.

Step 6: Bake to Perfection

Cover the dish with foil and bake for 25-30 minutes.

Remove the foil and continue baking for an additional 5-10 minutes until the top is bubbly and golden.

For extra browning, pop it under the broiler for 1-2 minutes.

Step 7: Finish and Serve

Sprinkle some extra parmesan cheese and fresh parsley on top.

Let it cool for a few minutes before serving to let the layers set and flavors mingle.

Best Tips for Cheesy Chicken Artichoke Layers

• Whisk milk gradually and steadily to prevent lumps, creating a silky-smooth white sauce base for your lasagna.
• Use roasted garlic instead of raw for a sweeter, more complex taste that enhances the entire dish's richness.
• Pat spinach and artichokes dry before adding to reduce excess moisture and maintain lasagna's structural integrity.
• Swap chicken with turkey, shredded rotisserie chicken, or plant-based protein for flexible dietary needs.
• Watch carefully during broiling to achieve golden-brown top without burning, checking every 30 seconds for perfect color.

Store and Reheat Spinach Artichoke Lasagna

• Store leftover lasagna in an airtight container within 2 hours of cooking, keeping it fresh for 3-4 days in the refrigerator.
• Wrap individual portions or the entire lasagna tightly in plastic wrap and aluminum foil, storing in the freezer for up to 3 months.
• Warm individual servings in the microwave for 2-3 minutes, stirring halfway through to ensure even heating.
• Thaw overnight in the refrigerator, then bake covered at 350°F for 20-25 minutes until heated completely through, removing foil for the last 5 minutes to restore crispy edges.

What Goes Great with Chicken Artichoke Lasagna

• Pair with Crisp White Wine: A chardonnay or sauvignon blanc cuts through the rich, creamy lasagna with its bright acidity and refreshing notes.
• Complement with Fresh Green Salad: A light arugula salad with lemon vinaigrette balances the lasagna's heaviness, adding zesty contrast and cleansing the palate.
• Match with Roasted Vegetable Side: Garlic-roasted asparagus or Brussels sprouts provide earthy undertones that enhance the chicken and artichoke flavors.
• Serve with Crusty Bread: Warm, rustic sourdough or ciabatta helps soak up the creamy sauce and adds a delightful textural element to the meal.

Recipe Variations for Chicken Artichoke Lasagna

• Vegetarian Version: Replace chicken with grilled portobello mushrooms or plant-based protein crumbles for a meat-free alternative that maintains the creamy, cheesy texture.
• Gluten-Free Option: Swap traditional lasagna noodles with gluten-free pasta sheets or zucchini slices, and use cornstarch instead of flour for thickening the sauce.
• Low-Carb Adaptation: Substitute noodles with thinly sliced eggplant or cauliflower sheets, reducing carbohydrate content while keeping the rich, savory flavors intact.
• Dairy-Free Alternative: Use coconut milk instead of regular milk, nutritional yeast in place of cheese, and dairy-free mozzarella to accommodate lactose-intolerant or vegan dietary needs.

FAQs

• Can I use frozen spinach instead of fresh?

Yes, use thawed and well-drained frozen spinach. Squeeze out excess moisture to prevent watery lasagna.

• Is it okay to substitute chicken with another protein?

Absolutely! Shredded turkey or rotisserie chicken work great. For vegetarian options, try white beans or tofu.

• What if I don't have fresh parsley for garnish?

No problem. Skip it or use dried parsley, chives, or green onions as alternative garnishes.

• How can I make this recipe more budget-friendly?

Use less expensive cheese like mozzarella and reduce the amount of parmesan. Rotisserie chicken is also a cost-effective protein option.

Cheesy Chicken, Spinach, And Artichoke Lasagna Recipe

---

5 Stars 4 Stars 3 Stars 2 Stars 1 Star

4.6 from 39 reviews

• Total Time: 1 hour 7 minutes
• Yield: 8 1x

Print Recipe

Pin Recipe

Description

Creamy cheesy chicken, spinach, and artichoke lasagna blends Mediterranean flavors into a comforting Italian classic. Layers of rich cheese, tender chicken, and earthy vegetables create a satisfying meal you’ll crave again and again.

---

Ingredients

Scale 1x2x3x

Main Ingredients:

• 3 cups (420g) rotisserie chicken, shredded
• 1/2 pound frozen chopped spinach, thawed and squeezed of excess liquid
• 1 can (15 ounces) artichoke hearts, drained and chopped
• 16 ounces (1 pound) lasagna noodles, cooked al dente

Cheese Category:

• 4 cups (452g) mozzarella cheese, shredded
• 1 cup (100g) parmesan cheese, grated
• 1 container (15 ounces) whole milk ricotta cheese

Sauce and Seasoning Ingredients:

• 3 tablespoons unsalted butter
• 1 1/2 teaspoons garlic, minced
• 3 tablespoons all-purpose flour
• 3 cups (735g) whole milk
• 1 teaspoon kosher salt
• 1/2 teaspoon black pepper

Garnish:

• Fresh parsley
• Grated parmesan

Cook Mode Prevent your screen from going dark

---

Instructions

1. Prepare the foundation for this luxurious lasagna by heating the oven to 375°F and generously coating a 9×13-inch baking dish with cooking spray.
2. Craft a velvety roux in a skillet by melting butter and sautéing minced garlic for one minute, then incorporating flour and cooking until fragrant.
3. Transform the roux into a creamy sauce by gradually whisking in milk, seasoning with salt and pepper, and simmering until the mixture thickens and coats the back of a spoon.
4. Enhance the sauce by stirring in parmesan cheese until completely melted and smooth.
5. Integrate shredded chicken, chopped spinach, and diced artichoke hearts into the creamy sauce, creating a rich and flavorful filling.
6. Construct the lasagna by layering components strategically: spread a thin layer of chicken mixture on the bottom of the baking dish, arrange lasagna noodles, dollop ricotta cheese, add another layer of chicken mixture, and sprinkle mozzarella.
7. Repeat the layering process, ensuring each layer is evenly distributed, and finish with a generous topping of mozzarella cheese.
8. Shield the lasagna with aluminum foil and bake for 25-30 minutes, allowing the flavors to meld and the noodles to become tender.
9. Remove the foil and continue baking for an additional 5-10 minutes until the cheese turns golden and the edges become bubbly.
10. For an optional crispy finish, broil the lasagna for 1-2 minutes, watching carefully to prevent burning.
11. Garnish with freshly grated parmesan and chopped parsley before serving, adding a final touch of flavor and visual appeal.

Notes

• Swap traditional noodles with zucchini strips or gluten-free lasagna sheets for a lower-carb or gluten-free alternative that maintains the creamy, rich flavor profile.
• Use rotisserie chicken or leftover grilled chicken to save time and add extra flavor complexity without additional cooking steps.
• Fresh spinach wilts faster and provides brighter color compared to frozen, so adjust cooking time and moisture levels accordingly when substituting ingredients.
• Create a vegetarian version by replacing chicken with extra firm tofu, mushrooms, or white beans while keeping the cheesy, creamy sauce intact for added protein.

• Prep Time: 25 minutes
• Cook Time: 35-42 minutes
• Category: Dinner
• Method: Baking
• Cuisine: Italian

Nutrition

• Serving Size: 8
• Calories: 570
• Sugar: 4g
• Sodium: 790mg
• Fat: 30g
• Saturated Fat: 18g
• Unsaturated Fat: 8g
• Trans Fat: 0g
• Carbohydrates: 48g
• Fiber: 2g
• Protein: 34g
• Cholesterol: 115mg